Rasionalitas Penggunaan Obat Antihipertensi di Puskesmas Pinang Jaya Kota Bandar Lampung
Abstract
Hypertension is blood pressure above 140/90 mm Hg. Hypertension patients at Pinang Jaya Health Center, Bandar Lampung City, are included in the 10 largest diseases which occupy the second highest number suffered by patients. The hypertension treatment cycle is quite long so it must be diagnosed early and treated appropriately. The purpose of this study was to determine the rational use of antihypertensive drugs in hypertensive patients at Pinang Jaya Health Center, Bandar Lampung City based on the right indication, the right diagnosis, the right drug, the right patient, the right dose, the right method of administration and the right time interval for administration. The method used in this study is retrospective which is non-experimental (observational). Data were taken from patient medical records during January-December 2022 and the sample obtained was 104 patients, most of whom were female as many as 85 (81.73%) and patients aged 56-65 years as many as 29 (27.88%). The groups of drugs prescribed were amlodipin 98 (94.23%), captopril 2 (1.92%) and the use of combination therapy drugs, namely amlodipin with captopril 4 (3.85%). The rational use of antihypertensive drugs that meet the rational category of the right diagnosis, the right drug, the right indication, the right patient, the right dose, the right method of administration and the right time interval for administration is 100%. The use of antihypertensive drugs for outpatients at Pinang Jaya Health Center, Bandar Lampung City is rational.
References
Adnyani, P., & Sudhana, I. 2015. Prevalensi Dan Faktor Risiko Terjadinya Hipertensi Pada Masyarakat Di Desa Sidemen, Kecamatan Sidemen, Karangasem Periode Juni-Juli 2014. E-Jurnal Medika Udayana, . Retrieved from https://ojs.unud.ac.id/index.php/eum/article/view/12899
Fares, H., DiNicolantonio, J. J., O'Keefe, J. H., & Lavie, C. J. 2016. Amlodipine in hypertension: a first-line agent with efficacy for improving blood pressure and patient outcomes. Open heart, 3 (2), e000473. https://doi.org/10.1136/openhrt-2016- 000473
Fernanda, S. A., Susanto, F. H., & Cesa, F. Y. 2023. Evaluasi Penggunaan Obat Antihipertensi di Rumah Sakit. Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas, 1(1).
James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., ... & Ortiz, E. 2014. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). Jama, 311(5), 507-520.
Kemenkes RI. 2011. Modul Penggunaan Obat Rasional Dalam Praktek. Kementerian Kesehatan Republik Indonesia, 3-4.
Kementerian Kesehatan Republik Indonesia. 2014. Retrieved 21 June 2023, from https://kemkes.go.id/article/view/15052900001/profil-kesehatan-indonesia-tahun-2014.html
Lestari,T. 2016. Asuhan Keperawatan Anak. Yogyakarta. Nuha Medika.
Mazaya, S. S., Rifkia, V., & Chairani, A. 2019. Perbandingan Penurunan Tekanan Darah Pasien Hipertensi Intradialisis dengan Obat Antihipertensi Amlodipin dan Kaptopril di RS Bhayangkara Tk. I R. Said Sukanto (Doctoral dissertation, Universitas Pembangunan Nasional Veteran Jakarta.
Nafrialdi, 2012, Efficacy and Safety of Pioglitazone in Type 2 Diabetes Mellitus: a postmarketing observational study., Acta medica Indonesiana, 44 (1), 28– 34. Terdapat di: http://www.ncbi.nlm.nih.gov/pubmed/22451182.
Pascual, J. 2000. Hypertension control in the elderly with amlodipine. Current medical research and opinion, 16(1), 33-36.
Priatmojo, P. A., & Anita, R. 2015. Gambaran Pemberian Obat Antihipertensi pada Lansia dengan dan tanpa Komplikasi RS Dustira Cimahi Tahun 2014. Prosiding Pendidikan Dokter, 607-615.
Puspitasari, C. E., Widiyastuti, R., Dewi, N. M. A. R., Woro, O. Q. L., & Syamsun, A. 2022. Profil Drug Related Problems (DRPs) pada Pasien Hipertensi di Instalasi Rawat Jalan Rumah Sakit Pemerintah di Kota Mataram Tahun 2018: Profile of Drug Related Problems (DRPs) on Hypertension in Outpatients Installation at one of Mataram Government Hospital in 2018. Jurnal Sains dan Kesehatan (J. Sains Kes.), 4(SE-1), 77-87.
Quan, A., Chavanu, K., & Merkel, J. 2006. A review of the efficacy of fixed-dose combinations olmesartan medoxomil/hydrochlorothiazide and amlodipine besylate/benazepril in factorial design studies. American journal of cardiovascular drugs, 6, 103-113.
RISKESDAS (Riset Kesehatan Dasar). 2018. Jakarta: Badan Penelitian dan Pengembangan Kesehatan, Departemen Kesehatan, Republik Indonesia.
Sa'idah, Dian 2018 Evaluasi rasionalitas penggunaan obat antihipertensi di Instalasi Rawat Jalan RSUD Dr. Soegiri Lamongan periode tahun 2017. Undergraduate thesis, Universitas Islam Negeri Maulana Malik Ibrahim.
Sica, D. A. 2002. Rationale for fixed-dose combinations in the treatment of hypertension: the cycle repeats. Drugs, 62, 443-462.
World Health Organization (WHO). 2019. Hypertension.
