Literature Riview: Potensi Antioksidan dan Antihiperglikemik In Vitro dan In Vivo dari Jamblang
Abstract
Antioxidants are one way to overcome the problem of free radicals. Diabetes is a group of metabolic diseases characterized by increased blood sugar levels and caused by impaired insulin secretion, impaired insulin action, or both. In vitro testing of glucose lowering activity was carried out using the Nelson-Somogyi method. Jamblang leaves are effective in normalizing glucose levels and controlling oxidative stress. This review aims to provide information regarding the potential of jamun as an antidiabetic drug so that it can be developed further. This research uses primary data sources. Collected through databases such as Google Scholar, several national journals can be searched as data sources. The results of this research indicate the presence of secondary metabolites such as alkaloids, flavonoids, saponins, terpenoids, tannins, steroids, phenolics, glycosides, cardiac glycosides, and resins in various plants, including bark, seeds, and leaves.
References
Aini, Q., et al. 2022. PHYTOCHEMICAL SCREENING OF METHANOL EXTRACT OF JAMBLANG (Syzygium Cumini L.) AS ANTIDIABETIC, Jurnal biologi sains dan kependidikan. 2, 227–232.
Indrisari, M. (2017). Antihyperglycemic Activity of Various Extracts of Jamblang (Syzygium Cumini) on White Rat. Journal of Pharmaceutical and Medicinal Sciences, 2(2), 81–84.
Maliza, N. O., Safrida, S., Hayuningtyas, A., & Ayunda, H. M. (2022). Literatur Review: Potensi Pengolahan Dan Manfaat Kesehatan Jamblang (Syzygium Cumini L.). Jurnal Teknologi Pengolahan Pertanian, 4(2), 72- 80.
Nisma, F., Situmorang, A., & Fajar, M. (2010). Uji Aktivitas Antioksidan Ekstrak Etanol 70% Bunga Rosella (Hibiscus sabdariffa L.) Berdasarkan Aktivitas SOD (Superoxyde Dismutase) dan Kadar MDA (Malonildialdehide) pada Sel Darah Merah Domba yang Mengalami Stres Oksidatif In Vitro. Farmasisains, 1(1).
Razak, A. R. R., Sumarni, N. K., & Rahmat, B (2012). Optimalisasi Hidrolisis Sukrosa Menggunakan Resin Penukar Kation Tipe Sulfonat. Natural Science: Journal of Science and Technology, 1(1).
Sari, A. N., Januardi, J., & Diningrat, D. S. 2020. Effect of Ethanol Extract of Jamblang Aceh (Syzygium cumini) in Diabetic Mice (Mus musculus) and Its Potential As Anti-Diabetic Agent. Elkawnie, 6(1), 37.
Silalahi, M. (2018). Jamblang (Syzygium Cumini (L.) Dan Bioaktivitasnya. Jurnal Terpadu Ilmu Kesehatan, 7(2), 124-132.
Tirzitis, G., & Bartosz, G. (2010). Determination of Antiradical and Antioxidant Activity: Basic Principles and New Insights. Acta Biochimica Polonica, 57(1), 139-142.
